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Radiation Biology

Radiation biology is a primary concept underlying the practice of radiation oncology, and understanding the principles of radiation biology is essential for radiation oncologists to understand the effects of radiation therapy on the body. All radiation oncology residents are required to take a qualifying board exam on radiation biology. The study guide from the American Board of Radiology Qualifying Examination in Radiation and Cancer Biology is a comprehensive question and answer guide that provides guidance on the content that is tested on the exam. On this page, we have included high-yield radiation biology review lectures and two full radiation biology courses for radiation oncology residents to use in their studying on this topic.

Radiobiology Lectures

2023 Review Videos

2020 Review Videos

Chicago Radiobiology Course by Gayle Woloschak, PhD (2020-2021)

Lecture NumberLecture SubjectYear
Lecture 1The Physics and Chemistry of Radiation Absorption2020-2021
Lecture 2DNA Strand Breaks and Chromosomal Aberrations2020-2021
Lecture 3Cell Survival Curves2020-2021
Lecture 4Radiosensitivity and Cell Age in the Mitotic Cycle2020-2021
Lecture 5Repair of Radiation Damage and the Dose-Rate Effect2020-2021
Lecture 6The Oxygen Effect and Reoxygenation2020-2021
Lecture 7LET and RBE2019-2020
Lecture 8 (Part 1)Acute Effects of Total Body Radiation2020-2021
Lecture 8 (Part 2)Radiologic Terrorism2020-2021
Lecture 9Radioprotectors2020-2021
Lecture 10Radiation Carcinogenesis2020-2021
Lecture 11Hereditary Effects of Radiation2020-2021
Lecture 12Effects of Radiation on Embryo and Fetus2020-2021
Lecture 13Radiation Cataractogenesis2020-2021
Lecture 14Doses and Risks in Diagnostic and Interventional Radiology2020-2021
Lecture 15Radiation Protection2020-2021
Lecture 16Cancer Biology2020-2021
Lecture 17Dose-Response Relationships for Normal Tissues2020-2021
Lecture 18Clinical Response of Normal Tissues2020-2021
Lecture 19Model Tumor Systems2020-2021
Lecture 20Cell, Tissue, and Tumor Kinetics2020-2021
Lecture 21Time, Dose, and Fractionation in Radiotherapy2020-2021
Lecture 22Alternative Treatment Modalities2020-2021
Lecture 23Radiosensitizers and Bioreductive Drugs2020-2021
Lecture 24Gene Therapy2020-2021
Lecture 25Chemotherapy and Radiation2020-2021
Additional Topic 1Radiation Sensitivity Syndromes and Molecular DNA Repair2020-2021
Additional Topic 2Hyperthermia2020-2021
Additional Topic 3Molecular Imaging2020-2021
Additional Topic 4Predictive Assays2020-2021

High-Yield Radiobiology Board Review by Gayle Woloschak, PhD

Radiobiology Review Course by William McBride, PhD, DSc.

The following lecture series from 2006 was provided courtesy of William McBride, PhD, DSc. The lectures cover core topics in radiobiology that are fundamental to radiotherapeutic management of cancer.

Interaction of Radiation With Biological MatterRadiation Targets 1Radiation Targets 2Molecular Signaling and CancerClinically Relevant Normal Tissue ResponsesTumor Responses to RadiotherapyRadiobiology Behind Dose FractionationThe Radiobiology of Alternate Physical Forms of Radiation DeliveryBiologic Targeting in Radiation TherapyInteractions of RT with CT and Other AgentsThe Effects of Radiation Exposure Inside and Outside the Clinic
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