ASTRO Guideline on Radiation Therapy for Glioblastoma
Published: July 2016 (Web posted March 2016)
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The guideline addresses the following four areas regarding effective treatment of glioblastoma with radiation therapy: 1) when radiation is indicated following biopsy or resection of glioblastoma and how it is impacted by systemic therapy; 2) optimal dose-fractionation schemes for EBRT following biopsy or section and whether pretreatment characteristics like age or performance status affect appropriate fractionation; 3) ideal target volumes for curative-intent EBRT; and 4) the role of reirradiation in patients whose disease returns after initial treatment.
Endorsed by:
- American Society of Clinical Oncology
Key Points:
- Ideal dose-fractionation and target volume design
- Tumor-specific and patient-specific factors, including cytogenetics, performance status, and age, and the potential role of re-irradiation in recurrence
Resources:
Imaging Brain Tumors: Practical Primer for the Radiation Oncologist (CME)
Challenging Cases to CNS Current Approaches (CME)
